{"product_id":"adequan-i-m-equine","title":"Adequan i.m. Equine","description":"\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eVeterinarian Prescription (Rx) Required\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ch4\u003e\u003cstrong\u003eThere is no generic equivalent\u003c\/strong\u003e\u003c\/h4\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eFDA-approved prescription injectable for the intramuscular treatment of non-infectious degenerative and\/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses\u003c\/li\u003e\n\u003cli\u003eContains 100 mg\/mL polysulfated glycosaminoglycan (PSGAG), a disease-modifying osteoarthritis drug (DMOAD)\u003c\/li\u003e\n\u003cli\u003eAdministered by intramuscular injection every 4 days for 28 days (7 total treatments)\u003c\/li\u003e\n\u003cli\u003eHelps support healthy cartilage, joint function, and mobility under veterinary supervision\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\n\u003ch2\u003e\u003cspan\u003eDescription\u003c\/span\u003e\u003c\/h2\u003e\n\u003cspan\u003eAdequan® i.m. is an FDA-approved prescription injectable medication containing polysulfated glycosaminoglycan (PSGAG) for the intramuscular treatment of non-infectious degenerative and\/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses. It is classified as a disease-modifying osteoarthritis drug (DMOAD) and is commonly incorporated into comprehensive veterinary treatment plans for equine joint disease.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eFollowing intramuscular administration, polysulfated glycosaminoglycan is distributed into synovial fluid and articular cartilage, where laboratory studies suggest it helps support normal cartilage metabolism and joint health. Research has shown PSGAG may inhibit certain enzymes involved in cartilage degradation while promoting the production of proteoglycans, collagen, and hyaluronic acid that contribute to healthy joint function. Although the exact mechanism of action in equine joints has not been fully established, Adequan i.m. has demonstrated clinical efficacy in horses with degenerative joint dysfunction.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eEarly treatment may help support long-term joint function and mobility. Adequan i.m. should be administered only under the direction of a licensed veterinarian.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\n\u003ch3\u003eUses \u0026amp; Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eFDA-approved for horses\u003c\/li\u003e\n\u003cli\u003eDisease-Modifying Osteoarthritis Drug (DMOAD)\u003c\/li\u003e\n\u003cli\u003eTreats non-infectious degenerative and traumatic joint dysfunction\u003c\/li\u003e\n\u003cli\u003eHelps control associated lameness of the carpal and hock joints\u003c\/li\u003e\n\u003cli\u003eSupports healthy cartilage metabolism\u003c\/li\u003e\n\u003cli\u003eHelps maintain normal joint lubrication\u003c\/li\u003e\n\u003cli\u003eSupports mobility and joint function\u003c\/li\u003e\n\u003cli\u003eIntramuscular injectable formulation\u003c\/li\u003e\n\u003cli\u003eConvenient every-4-day dosing schedule\u003c\/li\u003e\n\u003cli\u003eVeterinarian-directed treatment\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cspan\u003eAdequan® i.m. contains polysulfated glycosaminoglycan (PSGAG), a semi-synthetic compound structurally similar to naturally occurring cartilage components.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eFollowing intramuscular injection, PSGAG reaches the synovial fluid and articular cartilage where laboratory studies have shown it may:\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eInhibit enzymes associated with cartilage degradation\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eSupport proteoglycan and collagen synthesis\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003ePromote hyaluronic acid production\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eHelp maintain normal cartilage structure\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eSupport healthy joint lubrication\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eThese combined actions help support healthy joint function and mobility in horses with degenerative joint disease. Although the precise mechanism has not been fully established, Adequan i.m. is classified as a disease-modifying osteoarthritis drug (DMOAD).\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\n\u003ch2\u003e\u003cspan\u003eIndications\u003c\/span\u003e\u003c\/h2\u003e\n\u003cspan\u003eAdequan® i.m. is indicated for:\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003eTreatment of non-infectious degenerative joint dysfunction\u003c\/li\u003e\n\u003cli\u003eTreatment of traumatic joint dysfunction\u003c\/li\u003e\n\u003cli\u003eControl of associated lameness\u003c\/li\u003e\n\u003cli\u003eManagement of joint dysfunction involving the carpal joints\u003c\/li\u003e\n\u003cli\u003eManagement of joint dysfunction involving the hock joints\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\u003cspan\u003eFor use in horses only.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eClinical Studies:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eClinical studies demonstrated that horses treated with Adequan® i.m. according to the approved dosing schedule showed significant improvement in clinical signs associated with degenerative joint dysfunction, including lameness. Laboratory studies also confirmed distribution of polysulfated glycosaminoglycan into synovial fluid following intramuscular administration, supporting its activity within affected joints. \u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\n\u003ch2\u003e\u003cspan\u003eIngredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cspan\u003eEach mL Contains\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003ePolysulfated Glycosaminoglycan (PSGAG) — 100 mg\u003c\/li\u003e\n\u003cli\u003eEach 5 mL Vial Contains\u003c\/li\u003e\n\u003cli\u003e500 mg PSGAG\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eInactive Ingredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cstrong\u003eSingle-Dose Vial\u003c\/strong\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003eWater for Injection\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong\u003eMulti-Dose Vial\u003c\/strong\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003eBenzyl Alcohol (Preservative)\u003c\/li\u003e\n\u003cli\u003eWater for Injection\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ch2\u003e\u003cspan\u003eDirections\u003c\/span\u003e\u003c\/h2\u003e\n\u003cspan\u003eUse only as directed by your veterinarian.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eAdminister by intramuscular injection only.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eRecommended Dose:\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e500 mg (5 mL) - Treatment Schedule\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003eOne intramuscular injection every 4 days\u003c\/li\u003e\n\u003cli\u003eContinue for 28 days\u003c\/li\u003e\n\u003cli\u003eTotal of 7 injections\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\u003cstrong\u003eDo not mix Adequan® i.m. with other drugs or solvents in the same syringe.\u003cbr\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eFor the multidose vial:\u003cbr\u003e\u003c\/strong\u003e\u003cspan\u003eUse within 28 days after first puncture.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eDo not puncture the stopper more than 10 times.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eWeight \u0026amp; Dosage\u003cbr\u003e\u003c\/strong\u003e\u003cspan\u003eAdult Horse - 5 mL (500 mg)\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eTreatment Schedule: (One injection every four days for seven total treatments.)\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eAdminister exactly as prescribed by your veterinarian. Follow all dosing and administration instructions provided on the prescription label and by your veterinarian. Do not adjust the dose or frequency unless directed by your veterinarian.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\n\u003ch2\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cspan\u003eThe safe use of Adequan® i.m. in breeding horses, pregnant mares, or lactating mares has not been established.\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003eUse sterile injection technique.\u003c\/li\u003e\n\u003cli\u003eThoroughly cleanse the injection site prior to administration.\u003c\/li\u003e\n\u003cli\u003eFollow your veterinarian's dosing schedule carefully.\u003c\/li\u003e\n\u003cli\u003eInform your veterinarian of any medications or supplements your horse is receiving.\u003c\/li\u003e\n\u003cli\u003eFederal law restricts this drug to use by or on the order of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003eFor use in horses only.\u003c\/li\u003e\n\u003cli\u003eFor animal use only.\u003c\/li\u003e\n\u003cli\u003eDo not use in horses intended for human consumption.\u003c\/li\u003e\n\u003cli\u003eNot for use in humans.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n\u003cli\u003eFor intramuscular injection only.\u003c\/li\u003e\n\u003cli\u003eDo not administer intra-articularly or intravenously.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\u003cbr\u003e\n\u003ch3\u003ePossible Side Effects\u003c\/h3\u003e\n\u003cspan\u003eAdverse reactions are uncommon when Adequan® i.m. is administered according to label directions.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eContact your veterinarian if your horse develops:\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003eInjection site swelling or irritation\u003c\/li\u003e\n\u003cli\u003ePersistent lameness\u003c\/li\u003e\n\u003cli\u003eAllergic reactions\u003c\/li\u003e\n\u003cli\u003eChanges in appetite or behavior\u003c\/li\u003e\n\u003cli\u003eAny unexpected clinical signs following treatment\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\u003cspan\u003eIn safety studies, horses receiving up to five times the recommended dose for three times the recommended treatment duration showed no clinical evidence of systemic toxicity.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\n\u003ch2\u003e\u003cspan\u003ePrecautions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cspan\u003eAdminister only by intramuscular injection.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eUse aseptic injection technique.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eDo not exceed the recommended dosage.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eMonitor horses throughout treatment.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eRepeat treatment only as directed by your veterinarian.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\n\u003ch2\u003e\u003cspan\u003eStorage\u003c\/span\u003e\u003c\/h2\u003e\n\u003cstrong\u003eSingle-Dose Vials:\u003cbr\u003e\u003c\/strong\u003e\u003cspan\u003eStore at 68°F to 77°F (20°C to 25°C). Discard unused portion after opening.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003eMulti-Dose Vial:\u003cbr\u003e\u003c\/strong\u003e\u003cspan\u003eStore at 68°F to 77°F (20°C to 25°C). Excursions permitted between 59°F and 86°F (15°C to 30°C). Avoid prolonged exposure to temperatures above 104°F (40°C). Use within 28 days of first puncture. Maximum 10 punctures per vial.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003eDisposal\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eDiscard any unused portion of single-dose vials. Dispose of expired or unused Adequan® i.m. according to applicable local requirements or veterinary medication disposal guidance. Dispose of used needles and other sharps in an appropriate sharps container in accordance with federal, state, and local requirements. Keep discarded medication, vials, needles, and packaging inaccessible to children and animals.\u003c\/span\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"shoppetx","offers":[{"title":"5 mL Single Dose - Vial","offer_id":54664087503123,"sku":null,"price":57.0,"currency_code":"USD","in_stock":true},{"title":"5 mL 7 Single Doses - Vials","offer_id":54664087535891,"sku":null,"price":399.0,"currency_code":"USD","in_stock":true},{"title":"50 mL Multi-Dose - Vial","offer_id":54664087568659,"sku":null,"price":519.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0936\/2853\/0963\/files\/3032-AdequanEquineSingle5mLVial.jpg?v=1788763260","url":"https:\/\/shoppetx.com\/es\/products\/adequan-i-m-equine","provider":"shoppetx","version":"1.0","type":"link"}