{"product_id":"nexgard-chewables-for-dogs","title":"NexGard Chewables for Dogs","description":"\u003ch2\u003e\u003cspan\u003eDescription\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eNexGard, which has demonstrated excellent efficacy at low dose, is the first and only soft beef-flavored chew approved to kill both fleas and ticks. It contains the novel active ingredient afoxolaner, an isoxazoline based compound with a new and distinct mode of action.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eBenefits \u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eIts irresistible beef flavor makes it easy to give\u003c\/li\u003e\n\u003cli\u003eIt kills fleas fast, before they lay eggs, preventing infestation\u003c\/li\u003e\n\u003cli\u003eAnd, it kills American dog Ticks, Lone star ticks, Black-legged (deer) ticks\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch2\u003e\u003cspan\u003eIndications\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eNexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eHow It Works\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eNexGard contains a brand new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, is rapidly absorbed into your pet's bloodstream where a good concentration makes your pet's blood toxic to insects without affecting your pet's health. The Afoxolaner is metabolized gradually to ensure that it remains in your pet's bloodstream in the appropriate concentration for a full 30 days.\u003c\/p\u003e\n\u003cp\u003eWhen a flea or tick attempts to feast on your pet's blood, Afoxolaner acts on their Central Nervous System by impeding an important neurotransmitter, which causes instantaneous death. This means your pet receives amazing protection in one tasty morsel! NexGard is a prescription-only medication, so talk to your veterinarian about using it for your pet.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2\u003e\u003cspan\u003eIngredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eNexGard Chewables for Small Dogs 4-10 lbs\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eActive Ingredient (per tablet)         \u003c\/td\u003e\n\u003ctd\u003eAmount \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e Afoxolaner \u003c\/td\u003e\n\u003ctd\u003e 11.3 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eNexGard Chewables - For Medium Dogs 10.1-24 lbs\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eActive Ingredient (per tablet)         \u003c\/td\u003e\n\u003ctd\u003eAmount \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAfoxolaner \u003c\/td\u003e\n\u003ctd\u003e28.3 mg\u003cbr\u003e\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eNexGard Chewables - For Large Dogs 24.1-60 lbs\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eActive Ingredient (per tablet)      \u003c\/td\u003e\n\u003ctd\u003eAmount \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e Afoxolaner\u003c\/td\u003e\n\u003ctd\u003e 68 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eNexGard Chewables - For Extra Large Dogs 60-121 lbs\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eActive Ingredient (per tablet)      \u003c\/td\u003e\n\u003ctd\u003e Amount \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e Afoxolaner  \u003c\/td\u003e\n\u003ctd\u003e 136 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eDirections\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eNexGard is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5 mg\/kg).\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eDosing Schedule\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eBody Weight \u003c\/td\u003e\n\u003ctd\u003eAfoxolaner Per Chewable (mg)            \u003c\/td\u003e\n\u003ctd\u003eChewables Administered \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e 4.0 to 10.0 lbs\u003c\/td\u003e\n\u003ctd\u003e 11.3\u003c\/td\u003e\n\u003ctd\u003e1 Orange \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e 10.1 to 24.0 lbs\u003c\/td\u003e\n\u003ctd\u003e 28.3\u003c\/td\u003e\n\u003ctd\u003e 1 Blue\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e 24.1 to 60.0 lbs\u003c\/td\u003e\n\u003ctd\u003e 68\u003c\/td\u003e\n\u003ctd\u003e 1 Purple\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e 60.1 to 121.0 lbs         \u003c\/td\u003e\n\u003ctd\u003e 136\u003c\/td\u003e\n\u003ctd\u003e 1 Red\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e Over 121.0 lbs\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e Administer the appropriate combination of chewables\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eNexGard can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard and resume a monthly dosing schedule.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eFlea Treatment and Prevention\u003c\/h3\u003e\n\u003cp\u003eTreatment with NexGard may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption.\u003c\/p\u003e\n\u003cp\u003eTo minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eTick Treatment and Control\u003c\/h3\u003e\n\u003cp\u003eTreatment with NexGard may begin at any time of the year (see Effectiveness).\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eContraindications\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eThere are no known contraindications for the use of NexGard.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eWarnings\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eNot for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003ePrecautions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eThe safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures (see Adverse Reactions).\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eAdverse Reactions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eIn a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard.\u003c\/p\u003e\n\u003cp\u003eOver the 90-day study period, all observations of potential adverse reactions were recorded. The most frequent reactions reported at an incidence of \u0026gt; 1% within any of the three months of observations are presented in the following table. The most frequently reported adverse reaction was vomiting. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eEffectiveness\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eIn a well-controlled laboratory study, NexGard began to kill fleas four hours after initial administration and demonstrated \u0026gt;99% effectiveness at eight hours. In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post-infestation through Day 21, and on Day 35. On Day 28, NexGard was 81.1% effective 12 hours post-infestation. Dogs in both the treated and control groups that were infested with fleas on Day -1 generated flea eggs at 12- and 24-hours post-treatment (0-11 eggs and 1-17 eggs in the NexGard treated dogs, and 4-90 eggs and 0-118 eggs in the control dogs, at 12- and 24-hours, respectively). At subsequent evaluations post-infestation, fleas from dogs in the treated group were essentially unable to produce any eggs (0-1 eggs) while fleas from dogs in the control group continued to produce eggs (1-141 eggs).\u003cbr\u003e\u003cspan\u003e \u003c\/span\u003eIn a 90-day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of NexGard against fleas on the Day 30, 60 and 90 visits compared with baseline was 98.0%, 99.7%, and 99.9%, respectively.\u003cbr\u003e\u003cspan\u003e \u003c\/span\u003eCollectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations.\u003cbr\u003e\u003cspan\u003e \u003c\/span\u003eIn well-controlled laboratory studies, NexGard demonstrated \u0026gt;97% effectiveness against Dermacentor variabilis, \u0026gt;94% effectiveness against Ixodes scapularis, and \u0026gt;93% effectiveness against Rhipicephalus sanguineus, 48 hours post-infestation for 30 days. At 72 hours post-infestation, NexGard demonstrated \u0026gt;97% effectiveness against Amblyomma americanum for 30 days.\u003c\/p\u003e","brand":"shoppetx","offers":[{"title":"4-10 lbs 3 Month - (orange)","offer_id":54663584842003,"sku":null,"price":91.39,"currency_code":"USD","in_stock":true},{"title":"4-10 lbs 6 Month - (orange)","offer_id":54663584874771,"sku":null,"price":160.89,"currency_code":"USD","in_stock":true},{"title":"4-10 lbs 12 Month - (orange)","offer_id":54663584907539,"sku":null,"price":321.78,"currency_code":"USD","in_stock":true},{"title":"10.1-24 lbs 3 Month - (blue)","offer_id":54663584940307,"sku":null,"price":93.29,"currency_code":"USD","in_stock":true},{"title":"10.1-24 lbs. 6 Month - (blue)","offer_id":54663584973075,"sku":null,"price":164.39,"currency_code":"USD","in_stock":true},{"title":"10.1-24 lbs 12 Month - (blue)","offer_id":54663585005843,"sku":null,"price":328.78,"currency_code":"USD","in_stock":true},{"title":"24.1-60 lbs 3 Month - (purple)","offer_id":54663585038611,"sku":null,"price":95.39,"currency_code":"USD","in_stock":true},{"title":"24.1-60 lbs 6 Month - (purple)","offer_id":54663585071379,"sku":null,"price":167.89,"currency_code":"USD","in_stock":true},{"title":"24.1-60 lbs 12 Month - (purple)","offer_id":54663585104147,"sku":null,"price":335.78,"currency_code":"USD","in_stock":true},{"title":"60.1-121 lbs 3 Month - (red)","offer_id":54663585136915,"sku":null,"price":96.29,"currency_code":"USD","in_stock":true},{"title":"60.1-121 lbs 6 Month - (red)","offer_id":54663585169683,"sku":null,"price":169.59,"currency_code":"USD","in_stock":true},{"title":"60.1-121 lbs 12 Month - (red)","offer_id":54663585202451,"sku":null,"price":339.18,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0936\/2853\/0963\/files\/553-NexGard.jpg?v=1788760131","url":"https:\/\/shoppetx.com\/es\/products\/nexgard-chewables-for-dogs","provider":"shoppetx","version":"1.0","type":"link"}