Rx Marquis Antiprotozoal Oral Paste x 127 gm tube

Marquis Antiprotozoal Oral Paste Marquis (15% w/w ponazuril) Antiprotozoal Oral is supplied in ready-to-use syringes containing 127 grams of paste. Each gram of paste contains 150 mg of ponazuril (15% w/w). Marquis (ponazuril) is designed to be delivered as an orally administered paste. Each syringe barrel of Marquis (ponazuril) contains enough paste to treat one (1) 1,200 lb (544 kg) horse seven (7) days, at a dose rate of 5 mg/kg (2.27 mg/lb) body weight. The plunger contains a dosage ring calibrated for a dose rate of 5 mg/kg (2.27 mg/lb) body weight and marked for horse weight from 600 to 1,200 lbs (272 to 544 kg). The syringe barrels are packaged in units of four with four reusable plungers. This package provides sufficient paste to trat one 1,200 lb (544 kg) horse for 28 days at a dose rate of 5 mg/kg (2.27 mg/lb) body weight. Marquis (ponazuril) is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by sarcocystis neurona. This product requires a prescription. All prescription items are Non-Refundable and Non-Returnable. - CAUTIONS/WARNINGS:Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of Marquis (ponazuril) in horses used for breeding purposes, during pregnancy, or in lactating mares, has not been evaluated. The safety of Marquis (ponazuril) with concomitant therapies in horses has not been evaluated. Warning: For use in animals only. Do not use in horses intended for human consumption. Keep out of reach of children and animals. All prescription items are Non-Refundable and Non-Returnable. - DIRECTIONS:Recommended dosages only. Always follow the directions for dosing and administration from your veterinarian. Marquis (15% w/w ponazuril) is to be used at a dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 28 days. Administration: Paste syringe assembly: Before administration, the syringe barrel and plunger require assembly. Ensure plunger is clean and dry. Step 1. End cap must be on syringe barrel when inserting plunger. Step 2. Carefully insert reusable plunger into base of syringe barrel until it snaps into place, then remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Step 3. Return end cap to tip of paste syringe. Administering Marquis (ponazuril) to the horse: NOTE: The paste syringe is a multi-dose package. Ensure that the correct dose is administered with each use. Step 1. Remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Return end cap to tip of paste syringe. Step 2. Determine weight of horse and insure the horse's mouth contains no feed. Step 3. To measure dose, dosage ring collar and barrel collar should be flush. Hold plunger and rotate dosage ring with the other hand to the weight of the horse. Step 4. Remove end cap from tip of syringe barrel. Step 5. The selected dose of paste should be deposited onto the back and top of the horse's tongue. Introduce tip of paste syringe into the side of the horse's mouth at the space between the front (incisor) and back (molar) teeth. Deposit paste on the horse's tongue by depressing the plunger of the syringe as far as the dose ring permits. Remove tip of syringe from horse's mouth. Step 6. To aid swallowing of paste, immediately raise horse's head for a few seconds after dosing. Step 7. Clean the tip of the syringe with a clean disposable towel and return end cap to tip of syringe barrel. Step 8. For the next daily dose, repeat steps 1-7. NOTE: At the end of the prescribed treatment period, partially used syringes should be discarded. Storage Conditions: Store at Controlled Room Temperature 15-30° C (59-86° F). - INGREDIENTS:Each gram of paste contains 150 mg of ponazuril (15% w/w). Marquis (ponazuril) is designed to be delivered as an orally administered paste. - MATERIAL/COMP:Paste - STORAGE/DISPOSAL REQ:Store at Controlled Room Temperature 15-30º C (59-86º F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000

Ingredients

Ponazuril 1,3,5-Triazine-2,4,6(1H, 3H, 5H)-trione,1-methyl-3-[3-methyl-4-[4-[(trifluoromethyl)sulfonyl] phenoxy]phenyl]-(9CI)

Dosage & Directions

Marquis (15% w/w ponazuril) is to be used at a dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 28 days. ADMINISTRATION: Paste syringe assembly: Before administration, the syringe barrel and plunger require assembly. Ensure plunger is clean and dry. Step 1. End cap must be on syringe barrel when inserting plunger. Step 2. Carefully insert reusable plunger into base of syringe barrel until it snaps into place, then remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Step 3. Return end cap to tip of paste syringe. Administering Marquis (ponazuril) to the horse: NOTE: The paste syringe is a multi-dose package. Ensure that the correct dose is administered with each use. Step 1. Remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Return end cap to tip of paste syringe. Step 2. Determine weight of horse and insure the horse’s mouth contains no feed. Step 3. To measure dose, dosage ring collar and barrel collar should be flush. Hold plunger and rotate dosage ring with the other hand to the weight of the horse. Step 4. Remove end cap from tip of syringe barrel. Step 5. The selected dose of paste should be deposited onto the back and top of the horse’s tongue. Introduce tip of paste syringe into the side of the horse’s mouth at the space between the front (incisor) and back (molar) teeth. Deposit paste on the horse’s tongue by depressing the plunger of the syringe as far as the dose ring permits. Remove tip of syringe from horse’s mouth. Step 6. To aid swallowing of paste, immediately raise horse’s head for a few seconds after dosing. Step 7. Clean the tip of the syringe with a clean disposable towel and return end cap to tip of syringe barrel. Step 8. For the next daily dose, repeat steps 1-7. NOTE: At the end of the prescribed treatment period, partially used syringes should be discarded.

Cautions & Warnings

For use in animals only. Not for use in horses intended for food. Not for human use. Keep out of the reach of children.

Storage & Disposal

Store at Controlled Room Temperature 15-30º C (59-86º F).